Quantification of low drug concentration in model formulations with multivariate analysis using surface enhanced Raman chemical imaging
نویسندگان
چکیده
منابع مشابه
Investigation of drug distribution in tablets using surface enhanced Raman chemical imaging.
This paper reports the first application of surface enhanced Raman chemical imaging on pharmaceutical tablets containing the active ingredient (API) in very low concentrations. Taking advantage of the extremely intensive Raman signals in the presence of silver colloids, image aquisition time was radically decreased. Moreover, the investigation of drug distribution below the detection limit of r...
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First, an effective pre-concentration of penicillamine was done via Fe3O4NPS. Then, a simple, rapid and sensitive spectrophotometric method is described for the determination of penicillamine by 2, 6-dichlorophenolindophenol (2, 6-DCPIP), as the chromogenic agent in bulk drug and formulations. It produces a bluish green coloured compound with maximum absorbance 610 nm. Bee...
متن کاملPre-concentration of Penicillamine using Fe3O4NPS and analysis of it in drug formulations through spectroscopic method
First, an effective pre-concentration of penicillamine was done via Fe3O4NPS. Then, a simple, rapid and sensitive spectrophotometric method is described for the determination of penicillamine by 2, 6-dichlorophenolindophenol (2, 6-DCPIP), as the chromogenic agent in bulk drug and formulations. It produces a bluish green coloured compound with maximum absorbance 610 nm. Bee...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical and Biomedical Analysis
سال: 2015
ISSN: 0731-7085
DOI: 10.1016/j.jpba.2014.12.039